Improving access for liver allocation
Making liver distribution more fair and equitable
About policy development
In its role as the Organ Procurement and Transplantation Network (OPTN), UNOS convenes the donation and transplant community to develop policies that provide fair and equitable access for patients to transplant. Many times during the past 30 years, these policies have been updated by the OPTN Board of Directors to balance the needs of patients nationwide and keep pace with the emerging science of transplantation.
For years, the system that matches donated livers with patients who need them was based on the inconsistent geographic boundaries of 57 donation service areas (DSAs) and 11 transplant regions. These areas of distribution vary widely in size, population density and concentration of donor and transplant hospitals. Over time, great disparities have developed in how sick liver candidates need to become in various parts of the country before they are likely to receive a transplant.
In its role as the OPTN, UNOS has been working for more than five years on a system to replace these inconsistent boundaries with a system that appropriately balances candidates’ medical urgency with the relative distance from their transplant hospital to a donor hospital.
New policy saves more lives
In December 2018, the OPTN board approved a new allocation system for liver transplantation. It is projected to save more lives annually, with fewer patients dying while waiting for a liver transplant. It also is expected to increase the number of pediatric liver transplants, making this a policy that will work more efficiently and fairly for patients across the entire country. The policy was developed by donation and transplant experts, recipients and donor families from around the country, with consideration of thousands of public comments.
Modeling shows that under the new system:
- Fewer people will die waiting
- More children will receive a transplant
- The geographic location of patients will be less important than how sick they are
How does it work?
DSA and regional boundaries were replaced by a sequence of circles in which we compare candidates’ degree of illness and the distance between donor hospital and their transplant hospital. It first prioritizes the very sickest liver candidates (Status 1A and 1B) listed at transplant hospitals within 500 nautical miles of the donor hospital. Following that, it prioritizes candidates of similar groupings of medical urgency—first those within 150 nautical miles, then those within 250 and 500 nautical miles.
Livers from deceased donors younger than age 18 are first offered to any candidates younger than age 18, listed at any transplant hospital within a 500 nautical-mile radius of the donor hospital, before any adult candidates of the same level of medical urgency.
Our mission is to unite and strengthen the donation and transplant community to save lives.
Facts about organ transplantation
- The national organ transplant system
- UNOS fast facts
- 2022 organ transplants again set annual records; organ donation from deceased donors continues 12-year record-setting trend
- FAQs about UNOS' role in the system
- Organ Procurement Organizations: Increasing organ donation
- Improving Organ Procurement and Oversight
- Improving access for liver allocation
- Improving access for kidney and pancreas allocation
- Executive Order on Advancing American Kidney Health
- UNOS LabsSM: Testing products, tools and methods to improve the transplant system
- In 2022, the U.S. reached 1 million transplants. But this is only the beginning.
For more information
Learn about how the new national liver transplant system makes allocation more equitable and saves more lives here.
Further information about the work and study that led to the OPTN Board of Directors’ adoption of a new system for liver distribution, including a narrated/animated illustration of the liver offer sequence, is available here.
A dynamic map showing relative distances from transplant hospitals to potential donor hospitals is available here.
A briefing paper that summarizes the proposal as adopted is available here.
Learn more about how we develop policy here.
UNOS is a non-profit, charitable organization that serves as the nation’s Organ Procurement and Transplantation Network (OPTN) under contract with the federal government. The OPTN helps create and define organ allocation and distribution policies that make the best use of donated organs. This process involves continuously evaluating new advances and discoveries so policies can be adapted to best serve patients waiting for transplants. All transplant programs and organ procurement organizations throughout the country are OPTN members and are obligated to follow the policies the OPTN creates for allocating organs.