in focus
Proportion of deceased donors with a history of IV drug use and death due to drug overdose during 2008 and 2018 by region

Based on data from the national Organ Procurement and Transplantation Network (OPTN).
If an organ donor is an active intravenous drug user, their risk of acute hepatitis C (HCV) infection is higher than almost any other behavioral risk factor.
The increasing opiate epidemic in the U.S. has impacted every region. Because of this tragedy, more transplants, especially those from donors that could place the potential recipient at increased risk of disease transmission, are being completed.
Though there is research detailing the successful use of organs from donors who are currently using and abusing drugs, challenges remain and clinicians and patients continue to be cautious, especially regarding the risks of inadvertently acquiring viral hepatitis and/or HIV.
Fortunately, hepatitis B remains relatively uncommon in the U.S. and unanticipated HIV transmissions have not been documented since the new Public Health Service (PHS) Increased Risk Guidelines were put into place in 2013. The safety and efficacy of HCV treatments in transplant is improving day by day, but according to cases studied in 2018 by the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC), unexpected hepatitis C (HCV) donor-derived transmissions have been on the rise.
Read more about the committee’s findings and an update on its work presented at the spring 2019 regional meetings.
In focus

New milestone reached in kidney donation and transplant
For the first time, more than 25,000 kidney transplants were performed in a single year

New animation for patients explains the lung Composite Allocation Score (CAS)
New patient-friendly video explains the factors that will determine lung allocation in the continuous distribution framework.

Another record year for heart transplants: Steep increases seen in DCD transplants in 2022
February is American Heart Month

More than 15,000 liver transplants performed in first two years of acuity circles policy
Two-year monitoring shows many states had volume changes within 10 percent of previous policy.