Brain-dead donors that fail conventional resuscitation measures as manifested by a poor cardiac output, inadequate organ perfusion pressures, and increasing lactic acidosis often respond to three-drug hormonal resuscitation (1).  Administration of a methylprednisilone bolus and infusions of arginine vasopressin and triiodothyronine to 701 brain-dead donors resulted in a 22.5% increase in the number of organs transplanted per donor(1).  Hormonal resuscitation was beneficial for donors both under, and over, age 40.  Hearts recovered from hormonal resuscitation donors have a significantly reduced 30 day mortality and a significant reduction in prolonged graft dysfunction (2).